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Protein Coding Gene : Pkn2 protein kinase N2
Primary Identifier  MGI:109211 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  109333
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable RNA polymerase binding activity; histone deacetylase binding activity; and protein serine/threonine kinase activity. Involved in apical junction assembly. Located in apical junction complex; cytoplasm; and nucleus. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human PKN2 (protein kinase N2).
PHENOTYPE: Mice homozygous for a null allele display embryonic lethality during organogenesis with impaired mesenchymal cell proliferation and neural crest cell migration. [provided by MGI curators]
  • synonyms:
  • serine/threonine kinase 7,
  • protein kinase C-like 2,
  • Stk7,
  • protein kinase C-like 2,
  • PRK2,
  • Prkcl2,
  • AI507382,
  • expressed sequence AI507382,
  • MGI:1925929,
  • RIKEN cDNA 6030436C20 gene,
  • MGI:2139749,
  • Pkn2,
  • MGD-MRK-38255,
  • 6030436C20Rik,
  • protein kinase N2
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Features --> Cross References

Genome

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1 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

10 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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