| Type | disruption phenotype | Description | Mice display an absence of interferon (IFN)-producing cells and show impaired IFN production in response to viral infection (PubMed:12461077). Complete absence of plasmacytoid dendritic cells (pDCs) and conventional CD8(+)-expressing dendritic cells (cDCs) (PubMed:12393690, PubMed:12538667, PubMed:23382217). Mice display reduced autoimmunity (PubMed:23382217). |
