Primary Identifier | MGI:3718071 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Slc2a4 |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was designed to insert loxP sites to flank exons 7-11 and insert a neomycin resistance cassette immediately downstream of exon 11. Protein expression is reduced in homozygous muscle and adipose tissue to 30% and 16 - 20% of wild-type, respectively. |