Primary Identifier | MGI:5829569 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Tert |
Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting vector is designed to insert a loxP site upstream of exon 1, including 1.5 kb of the promoter sequence, and an FRT-flanked neomycin resistance cassette, followed by a second loxP site, downstream of exon 2. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 1 and 2 floxed. |