| Primary Identifier | MGI:6194209 | Allele Type | Transgenic |
| Attribute String | Transactivator | Gene | Tg(Esr1-rtTA)1Blpn |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgene comprises the following elements: The mouse estrogen receptor 1 alpha promoter (4 kb genomic sequence upstream of ATG translation start), beta globin intron 1, the rtTA (reverse tetracycline-controlled transactivator) gene and SV40 poly(A) signal. This is part of the Tet-On system where mice double-transgenic for this transgene and a second transgene controlled by the tetO promoter express the second transgene in cells where the promoter of the first transgene is active when administered doxycycline. |
