Primary Identifier | MGI:6200234 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Mlh1 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced T to C transition at base pair 111,271,410 (v38) on chromosome 9, or base pair 377 in the GenBank genomic region NC_000075 encoding Mlh1. The mutation corresponds to residue 199 in the mRNA sequence NM_026810 within exon 1 of 19 total exons. The mutation results in a cysteine to arginine substitution at position 39 (C39R) in the MLH1 protein. |