Primary Identifier | MGI:5752611 | Allele Type | Targeted |
Gene | Malt1 | Transmission | Germline |
Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 11 was replaced with a floxed neomycin resistance cassette and a modified exon 11 in which nucleotide substitution (TGT CGC to GCG CGC) results in the amino acid substitution of cysteine with alanine at position 472 (C472A) and a silent mutation at codon 473. Cre-mediated recombination removed the selection cassette. |