Primary Identifier | MGI:1888498 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 57249 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable GABA-A receptor activity and neurotransmitter receptor activity. Predicted to contribute to chloride channel activity. Predicted to be involved in chemical synaptic transmission; chloride transmembrane transport; and regulation of membrane potential. Predicted to act upstream of or within chloride transport and gamma-aminobutyric acid signaling pathway. Predicted to be located in postsynaptic membrane. Predicted to be part of GABA-A receptor complex and transmembrane transporter complex. Predicted to be active in neuron projection; plasma membrane; and synapse. Is expressed in several structures, including brain; eye; genitourinary system; immune system; and liver and biliary system. Orthologous to human GABRQ (gamma-aminobutyric acid type A receptor subunit theta). PHENOTYPE: Males hemizygous for a mutation in this gene exhibit decreased prepulse inhibition. [provided by MGI curators] |