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Allele : Igf1<tm1Ts> insulin-like growth factor 1; targeted mutation 1, Timothy Stewart

Primary Identifier  MGI:1857466 Allele Type  Targeted
Attribute String  Null/knockout Gene  Igf1
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette was inserted into exon 3 after codon 15. This mutation inserts multiple stop codons into all reading frames of the B chain of the encoded protein. RT-PCR analysis demonstrated that the transcript is undetectable in homozygous animals.
  • mutations:
  • Insertion
  • synonyms:
  • IGF-I<->,
  • IGF-I<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

32 Publication categories

Trail: Allele