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Allele : Foxp3<tm5.2Ayr> forkhead box P3; targeted mutation 5.2, Alexander Y Rudensky

Primary Identifier  MGI:4430232 Allele Type  Targeted
Attribute String  Modified regulatory region, Null/knockout, Reporter Gene  Foxp3
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Two loxP sequences flanking conserved non-coding sequence 1 (CNS1 (Rr123)), in intron 1, as well as an FRT site flanked neomycin resistance gene cassette were inserted by homologous recombination. In addition, an EGFP cassette was inserted in-frame into the first coding exon. The selection cassette and the CNS were removed by flp- and cre-mediated recombination.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Foxp3<deltaCNS1gfp>,
  • Foxp3<deltaCNS1gfp>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

12 Publication categories

Trail: Allele