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Allele : Trp53<tm3Att> transformation related protein 53; targeted mutation 3, Laura D Attardi
Primary Identifier  MGI:5140077 Allele Type  Targeted
Attribute String  Conditional ready, Null/knockout Gene  Trp53
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site flanked puromycin resistance gene/transcription stop cassette was inserted into intron 1 and mutations were created in exon 4 altering codon 53 from phenylalanine to glutamine (p.F53Q) and codon 54 from phenylalanine to serine (p.F54S). The second transactivation domain is incapacitated once the stop sequences are removed by cre expression.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • p53<LSL-53,54>,
  • p53<LSL-53,54>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele




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