| Type | MGI:General | Description | whereas whole-kidney Na+ reabsorption (TNa) is normal, kidney oxygen consumption (QO2) is 80% higher, resulting in a nearly 40% lower TNa/ QO2 ratio relative to that in wild-type controls at baseline, intrarenal PO2 levels are lower in the outer medulla but normal in the cortex relative to wild-type controls after treatment with furosemide, mice show a 2.7-fold higher increase of PO2 levels in the outer medulla than wild-type controls, such that differences in PO2 levels are no longer significant |
