First Author | Hiraoka Y | Year | 1999 |
Journal | Biochim Biophys Acta | Volume | 1447 |
Issue | 2-3 | Pages | 291-7 |
PubMed ID | 10542329 | Mgi Jnum | J:58253 |
Mgi Id | MGI:1347138 | Doi | 10.1016/s0167-4781(99)00160-8 |
Citation | Hiraoka Y, et al. (1999) PLP-I: a novel prolactin-like gene in rodents. Biochim Biophys Acta 1447(2-3):291-7 |
abstractText | In this report, we describe molecular cloning and characterization of cDNAs encoding a novel rat prolactin-like protein. The rat cDNAs were isolated from the decidua and the gene was named PLP-I. cDNAs for the mouse equivalent were also cloned by the cross-hybridization technique. Pregnancy-specific expression of the rat PLP-I gene was observed in the rat placenta by Northern analysis. Location of signal peptide cleavage sites in rat and mouse pre-PLP-I proteins was predicted using a theoretical method. A molecular phylogenetic tree for the growth hormone-prolactin superfamily including the novel member, PLP-I, constructed using the neighbor-joining method, places rat/mouse PLP-I closest to rat/mouse placental lactogen I and II. |