Primary Identifier | MGI:2678005 | Allele Type | Targeted |
Attribute String | Humanized sequence, Null/knockout | Gene | Apc |
Inheritance Mode | Dominant | Transmission | Germline |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A frameshift mutation was introduced at codon 1309 via homolgous recombination, a most common germline mutation for human families susceptible to familial adenomatous polyposis coli (FAP). |