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Allele : Apc<tm2Tno> APC, WNT signaling pathway regulator; targeted mutation 2, Tetsuo Noda

Primary Identifier  MGI:2678005 Allele Type  Targeted
Attribute String  Humanized sequence, Null/knockout Gene  Apc
Inheritance Mode  Dominant Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  A frameshift mutation was introduced at codon 1309 via homolgous recombination, a most common germline mutation for human families susceptible to familial adenomatous polyposis coli (FAP).
  • mutations:
  • Insertion
  • synonyms:
  • APC 1309,
  • APC 1309,
  • APC1309,
  • Apcdelta1309,
  • Apcdelta1309,
  • Apc<1309>,
  • APC1309,
  • Apc<1309>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

10 Publication categories

Trail: Allele