Primary Identifier | MGI:5752873 | Allele Type | Targeted |
Gene | Dnmt1 | Transmission | Germline |
Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 13 was replaced with a floxed neomycin resistance cassette and a modified exon 13 in which nucleotide substitutions replaced two lysines with alanine within the conserved region of the intrisically disordered domain (IDD). Cre-mediated recombination removed the selection cassette. |