Primary Identifier | MGI:2655714 | Allele Type | Targeted |
Attribute String | Modified isoform(s), Null/knockout | Gene | Rpgrip1 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by insertion of a large cassette containing 3 duplicated exons and a neomycin resistance gene. RT-PCR and sequence analysis of mRNA from homozygous mutant animals detected a premature stop codon. Absence of gene expression in homozygous animals was confirmed by Western blot analysis. |