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Protein Coding Gene : Rere arginine glutamic acid dipeptide (RE) repeats

Primary Identifier  MGI:2683486 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  68703
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables transcription coactivator activity and transcription corepressor activity. Acts upstream of or within chromatin remodeling and nervous system development. Located in nucleus. Part of histone deacetylase complex. Is expressed in several structures, including alimentary system; eye; genitourinary system; nervous system; and vibrissa. Orthologous to human RERE (arginine-glutamic acid dipeptide repeats).
PHENOTYPE: Mice homozygous for disruptions in this gene display embryonic lethality with abnormalities in neural tube development, somite development, and in the embryonic heart. Mice homozygous for an ENU-induced allele exhibit narrow snouts, decreased body weight, renal agenesis and small eyes. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI414665,
  • eyes3,
  • RIKEN cDNA 1110033A15 gene,
  • MGI:3577417,
  • expressed sequence AW742570,
  • 1110033A15Rik,
  • MGI:1915953,
  • MGI:2140608,
  • mKIAA0458,
  • AW742570,
  • MGI:2140258,
  • arginine glutamic acid dipeptide (RE) repeats,
  • AI414665,
  • Rere,
  • Atr2,
  • eyes 3,
  • eye<m03Jus>,
  • eye03,
  • atrophin-2

Features --> Cross References

Genome

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1 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

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Disease

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