| First Author | Jacob CO | Year | 1992 |
| Journal | Reg Immunol | Volume | 4 |
| Issue | 5 | Pages | 298-304 |
| PubMed ID | 1290749 | Mgi Jnum | J:22359 |
| Mgi Id | MGI:66630 | Citation | Jacob CO (1992) Genetic variability in tumor necrosis factor production: relevance to predisposition to autoimmune disease. Reg Immunol 4(5):298-304 |
| abstractText | Rather than being involved merely in the effector arm of inflammatory processes that contribute to autoimmune organ destruction, a primary involvement of TNF may be in some of the more basic mechanisms that occur in autoimmune disease. In this review, data are presented on TNF-alpha that suggest the involvement of this cytokine in the genetic predisposition to autoimmune diseases such as lupus nephritis. |
