| Primary Identifier | IPR041249 | Type | Domain |
| Short Name | HEPN_DZIP3 |
| description | This entry represents the DZIP3-like HEPN nuclease domain. It has been found fused to TPR, Zn-ribbon, RING, Ankyrin, CARD, NACHT ATPase, DEATH and LRR in various animal lineages [].DZIP3 is a RNA-binding ubiquitin-protein ligase that targets H2AK119 (lysine 119 of histone H2A) [, ]. It interacts with CARM1 (coactivator-associated arginine methyltransferase 1) through its RING domain and may act as a coactivator of ERalpha target gene expression []. |
