Primary Identifier | MGI:2682211 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 381489 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables hormone binding activity. Acts upstream of or within several processes, including lung connective tissue development; myofibroblast differentiation; and nipple morphogenesis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in brain and metanephros. Orthologous to human RXFP1 (relaxin family peptide receptor 1). PHENOTYPE: Mice homozygous for disruptions in this gene display reduced male fertility, particularly at younger ages and early generations. Impaired nipple development prevents nursing by females. [provided by MGI curators] |