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Allele : Prph2<tm2.1Itl> peripherin 2; targeted mutation 2.1, inGenious Targeting Laboratory

Primary Identifier  MGI:6367783 Allele Type  Targeted
Attribute String  Not Specified Gene  Prph2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Two point mutations were introduced to exon 2 of the gene. The first was a silent G>A to eliminate a Hha1 restriction site to aid in genotyping, and the second was the A>G missense mutation to produce the p.N229S substitution in the encoded protein. An FRT site flanked neomycin selection cassette was removed via flp-mediated recombination.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Prph2<N>,
  • N229S-RDS,
  • Prph2<N>,
  • N229S-RDS
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele