| Primary Identifier | IPR004301 | Type | Family |
| Short Name | Nucleoplasmin |
| description | The nucleoplasmin family includes nucleophosmin, nucleoplasmin and nucleoplasmin-like proteins. Nucleophosmin (also known as NPM1/B23) is a multifunctional protein that is involved in a number of cellular activities, such as ribosome maturatation and export, centrosome duplication, and response to stress stimuli []. Nucleoplasmin (NPM2) is a histone chaperone for histones H2A-H2B and is highly expressed in the oocyte and through the early stages of embryogenesis [].Mutations of the NPM1 gene has been linked to acute myeloid leukemia []. |
