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Protein Coding Gene : Plekhm2 pleckstrin homology domain containing, family M (with RUN domain) member 2

Primary Identifier  MGI:1916832 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  69582
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable kinesin binding activity. Predicted to be involved in several processes, including Golgi organization; lysosome localization; and natural killer cell mediated cytotoxicity. Predicted to be located in lysosomal membrane. Predicted to be active in endosome membrane. Orthologous to human PLEKHM2 (pleckstrin homology and RUN domain containing M2).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased leukocyte numbers and decreased susceptibility to Salmonella infection. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2310034J19 gene,
  • 2310034J19Rik,
  • pleckstrin homology domain containing, family M (with RUN domain) member 2,
  • AI854247,
  • MGI:2140397,
  • expressed sequence AI854247,
  • Plekhm2

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For