Primary Identifier | MGI:3052159 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Ezr |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | LoxP sites were inserted to flank exons 3-5. An FRT-flanked promoterless Beta-galactosidase-neomycin cassette was inserted into intron 5. Crossing to mice expressing Flp recombinase in the germ line excises the FRT-flanked Beta-geo, leaving the loxP sites surrounding exons 3-5 and a single FRT site in intron 5. |