Primary Identifier | MGI:2157015 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Rasgrf1 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A genomic fragment containing exons 3-5 was replaced with a neomycin selection cassette. This region encodes the exchange-factor catalytic domain. Western blot analysis on brain extracts of homozygous mice indicated that no detectable protein was produced from this allele. |