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Allele : Rasgrf1<tm1Kln> RAS protein-specific guanine nucleotide-releasing factor 1; targeted mutation 1, Rudiger Klein

Primary Identifier  MGI:2157015 Allele Type  Targeted
Attribute String  Null/knockout Gene  Rasgrf1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A genomic fragment containing exons 3-5 was replaced with a neomycin selection cassette. This region encodes the exchange-factor catalytic domain. Western blot analysis on brain extracts of homozygous mice indicated that no detectable protein was produced from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Ras-GRF1-KO,
  • Ras-GRF -,
  • Ras-GRF -,
  • Ras-GRF1-KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

13 Publication categories

Trail: Allele