| Primary Identifier | MGI:6294768 | Allele Type | Targeted |
| Attribute String | Hypomorph | Gene | Atxn7 |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exons 3 and 4 as well as flanking intron containing GC-rich region upstream of exon 3 (2.4 kb total) are replaced with a PGK-neomycin cassette via homologous recombination. This removed the first 117 amino acids of the encoded protein. A truncated protein is expressed at approximately 50% normal levels. |
