| Type | MGI:General | Description | mice infected subcutaneously with the human pathogenic group A streptococcus (GAS) strain UMAA2616 exhibit 75% of mortality unlike similarly treated wild-type mice that exhibit 20% mortality mice infected subcutaneously with GAS strain MGAS166 exhibit 35% to 100% of mortality unlike similarly treated wild-type mice that exhibit 30% mortality mice infected subcutaneously with PAM-expressing GAS strain AP53 exhibit 80% mortality compared to 20% in similarly treated wild-type mice mice infected subcutaneously with GAS exhibit increased bacterial colonies in the spleen compared to similarly infected wild-type mice |