Primary Identifier | MGI:3050678 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Plxnd1 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The first coding exon, containing the sema domain, was replaced with a floxed neo. Southern blot demonstrated correct targeting. In situ hybridization and immunohistochemistry indicated lack of transcript and protein, respectively, in mutant embryos and hearts. |