Primary Identifier | MGI:5550062 | Allele Type | Targeted |
Gene | Rho | Transmission | Germline |
Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Using the human sequence, a knock-in was constructed that modifies the wild-type sequence to replace the stop codon with glutamic acid at position 349 (X349E) thereby adding a 51 amino acids to the protein. Cre-mediated recombination removed the Hprt selection cassette. |