Primary Identifier | MGI:2445946 | Allele Type | Chemically induced (ENU) |
Gene | Kitl | Inheritance Mode | Semidominant |
Strain of Origin | 101/Rl | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Nucleotide sequencing of Taq-generated RT-PCR products showed that this allele comprises a T-to-C transition. This eliminates exon 4 splice donor site G-GT by changing it to G-GA and produces an mRNA splicing defect through the use of a cryptic splice donor 8 bp downstream. There is little or no expression of wild-type mRNA. |