| First Author | Morita A | Year | 1994 |
| Journal | Biol Trace Elem Res | Volume | 42 |
| Issue | 2 | Pages | 165-77 |
| PubMed ID | 7981006 | Mgi Jnum | J:20186 |
| Mgi Id | MGI:68296 | Doi | 10.1007/BF02785387 |
| Citation | Morita A, et al. (1994) The effect of aging on the mineral status of female mice. Biol Trace Elem Res 42(2):165-77 |
| abstractText | To clarify the effect of aging on the mineral status of female mice, mineral concentrations in their tissues were determined. Five 2-mo-old, five 6-mo-old, and five 10-mo-old female B10BR mice were fed a commercial diet. Iron, zinc, copper, calcium, magnesium, sodium, and potassium concentrations in the blood, liver, kidney, heart, brain, lung, and spleen of the mice were determined using a flame atomic absorption spectrophotometer. Iron concentrations in the liver, kidney, heart, brain, and spleen increased with age. Significant differences were detected between mice 2 and 6 mo of age and between mice 2 and 10 mo of age. Zinc concentrations in the heart and lung decreased significantly with age. Zinc concentrations in the heart and lung of 10-mo-old mice were significantly lower than those of 2-mo-old mice. It is noteworthy that the copper concentration in the brain of 10-mo-old mice was markedly higher compared with that of younger mice. Calcium accumulation was apparent in the kidney of mice at 10 mo. |
