Primary Identifier | MGI:2446031 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(SFTPC-MST1R)71Mhw |
Strain of Origin | (C57BL/6 x C3H)F1 | Is Recombinase | false |
Is Wild Type | false |
description | Three transgenic founder lines were established. Founder #35 carries 8 copies of the transgene, founder #36 carries 3 copies, and founder #71 carries 12 copies. |
molecularNote | The transgene consists of a human MST1R cDNA cloned between a human SFTPC promoter and SV40 polyadenylation signal. 3.7 kb of human SFTPC promoter sequences drives transgene expression in the lungs. Western blot analysis shows high transgene expression in the lung and no other tissues examined. |