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Protein Coding Gene : Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
Primary Identifier  MGI:1201670 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  19185
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable identical protein binding activity; molecular adaptor activity; and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Part of proteasome accessory complex. Is expressed in brain; liver; and surface ectoderm. Orthologous to human PSMD4 (proteasome 26S subunit ubiquitin receptor, non-ATPase 4).
PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality and abnormal embryogenesis. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-36380,
  • multiubiquitin-chain-binding protein,
  • Mcb1,
  • anti secretory factor 1,
  • Af1,
  • MGI:107803,
  • angiocidin,
  • Psmd4,
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
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Features --> Cross References

Genome

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2 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

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Interactions

122 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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