First Author | Dan I | Year | 2000 |
Journal | FEBS Lett | Volume | 469 |
Issue | 1 | Pages | 19-23 |
PubMed ID | 10708748 | Mgi Jnum | J:60996 |
Mgi Id | MGI:1354211 | Doi | 10.1016/s0014-5793(00)01247-3 |
Citation | Dan I, et al. (2000) Molecular cloning of MINK, a novel member of mammalian GCK family kinases, which is up-regulated during postnatal mouse cerebral development. FEBS Lett 469(1):19-23 |
abstractText | A new germinal center kinase (GCK) family kinase, Misshapen/NIKs-related kinase (MINK), has been cloned and its expression has been characterized in several tissues and various developmental stages of the mouse brain. MINK encodes a 1300 amino acid polypeptide, consisting of an N-terminal kinase domain, a proline-rich intermediate region, and a C-terminal GCK homology region. The expression of MINK is up-regulated during the postnatal development of the mouse brain. MINK activates the cJun N-terminal kinase and the p38 pathways. |