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Interaction Term : transmission electron microscopy [MI:0020] PSI Molecular Interactions

Description  Microscopy technique in which a beam of electrons is transmitted through a sample to form an image. Samples can be purified molecules, for which no staining is required in order to detect interaction, or tissue/cells. In the latter case, during the treatment for microscope analysis a tissue section is incubated with high-specificity antibodies coupled to heavy metals (e.g. gold). Any tissue section can then be analysed by electron microscopy to localise the target proteins within the cell. This method supports very high resolution colocalisation of different molecules in a cell. Namespace  PSI-MI
Obsolete  false
  • synonyms:
  • tem
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Ontology Term --> All ancestors

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