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Interaction Term : microscale thermophoresis [MI:1247] PSI Molecular Interactions

Description  Measurement of the directed movement of particles in a microscopic temperature gradient. Any change of the hydration shell of biomolecules due to changes in their structure/conformation results in a relative change of movement along the temperature gradient and is used to determine binding affinities, binding kinetics and activity kinetics. Events such as the phosphorylation of a protein or the binding of small molecules to a target can be monitored. Namespace  PSI-MI
Obsolete  false
  • synonyms:
  • mst
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