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Publication : E17241 as a Novel ABCA1 (ATP-Binding Cassette Transporter A1) Upregulator Ameliorates Atherosclerosis in Mice.

First Author  Xu (???) Y Year  2021
Journal  Arterioscler Thromb Vasc Biol Volume  41
Issue  6 Pages  e284-e298
PubMed ID  33441025 Mgi Jnum  J:362652
Mgi Id  MGI:8158089 Doi  10.1161/ATVBAHA.120.314156
Citation  Xu Y, et al. (2021) E17241 as a Novel ABCA1 (ATP-Binding Cassette Transporter A1) Upregulator Ameliorates Atherosclerosis in Mice. Arterioscler Thromb Vasc Biol 41(6):e284-e298
abstractText  Reverse cholesterol transport, removing excess cholesterol from peripheral tissues, is an important therapeutic target for atherosclerosis treatment. In this study, we propose a new small molecule, E17241, that may be used to treat atherosclerosis by promoting reverse cholesterol transport via ABCA1 (ATP-binding cassette transporter A1) upregulation.
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