| Primary Identifier | MGI:2182368 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 170755 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables molecular adaptor activity and protein serine/threonine kinase activity. Acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand. Located in cytoplasmic vesicle. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Orthologous to human C8orf44-SGK3 (C8orf44-SGK3 readthrough) and SGK3 (serum/glucocorticoid regulated kinase family member 3). PHENOTYPE: Mutations in this gene result in wavy vibrissae and coat/hair anomalies due to impaired hair follicle development and/or hair cycle defects. Homozygotes for a null allele show increased food intake and fecal K+ excretion and reduced intestinal glucose transport and fasting plasma glucose levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
