| Primary Identifier | MGI:99632 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 98741 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including delayed rectifier potassium channel activity; protein heterodimerization activity; and transmembrane transporter binding activity. Predicted to be involved in action potential; potassium ion transmembrane transport; and protein localization to plasma membrane. Predicted to be located in neuronal cell body membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in dendrite; membrane; and neuronal cell body. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system gland; liver; and sensory organ. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human KCNB2 (potassium voltage-gated channel subfamily B member 2). PHENOTYPE: Mice homozygous for a targeted mutation exhibit neurological abnormalities when compared with controls, including an abnormal sleep/wake cycle, decreased exploratory and locomotor activity, and a motor strength deficit. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
