Primary Identifier | MGI:1925331 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 78081 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium channel regulator activity. Acts upstream of or within binding activity of sperm to zona pellucida and regulation of acrosome reaction. Predicted to be active in extracellular space. Orthologous to human CRISP1 (cysteine rich secretory protein 1). PHENOTYPE: Mice homozygous for a null mutation display an impaired acrosome reaction in response to progesterone but are fertile with normal testis morphology and weight. [provided by MGI curators] |