Primary Identifier | MGI:2153466 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 226896 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within inferior colliculus development; negative regulation of neuron apoptotic process; and positive regulation of transcription by RNA polymerase II. Part of transcription regulator complex. Is expressed in several structures, including brain; ganglia; genitourinary system; heart; and retina. Orthologous to human TFAP2D (transcription factor AP-2 delta). PHENOTYPE: Mice homozygous for a knock-out allele exhibit loss of inferior colliculus due to apoptosis. [provided by MGI curators] |