| Primary Identifier | MGI:2441837 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 210933 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GTPase activator activity. Involved in regulation of dendrite morphogenesis; regulation of synapse maturation; and regulation of synapse pruning. Acts upstream of or within several processes, including motor learning; neuron remodeling; and positive regulation of synapse assembly. Located in postsynapse and synaptic cleft. Is active in cerebellar climbing fiber to Purkinje cell synapse and postsynaptic density membrane. Is expressed in several structures, including brain; lung; skeletal muscle; and testis. Orthologous to human ADGRB3 (adhesion G protein-coupled receptor B3). PHENOTYPE: Mice homozygous for a conditional allele activated in Purkinje cells exhibit impaired motor learning with alterned climbing fiber electrophysiology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
