| Primary Identifier | MGI:1921958 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 74708 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein-folding chaperone binding activity. Acts upstream of or within axonemal dynein complex assembly and flagellated sperm motility. Located in cytoplasm. Is expressed in spermatid; spermatocyte; and testis. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 36. Orthologous to human DNAAF6 (dynein axonemal assembly factor 6). PHENOTYPE: Mice homozygous for a null allele develop normally but display male infertility associated with asthenozoospermia and abnormal sperm flagellum morphology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
