| Primary Identifier | MGI:2442507 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 226970 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable guanyl-nucleotide exchange factor activity and protein domain specific binding activity. Predicted to be involved in filopodium assembly and lamellipodium assembly. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in spinal cord and ventricular layer. Orthologous to human ARHGEF4 (Rho guanine nucleotide exchange factor 4). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased angiogenesis, vascular endothelial cell migration, tumor growth, and tumor vascularization. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
