Primary Identifier | MGI:109232 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 18143 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity. Involved in several processes, including positive regulation of behavioral fear response; regulation of gene expression; and response to redox state. Acts upstream of or within circadian sleep/wake cycle and locomotor rhythm. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of CLOCK-BMAL transcription complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; intestine; and retina. Orthologous to human NPAS2 (neuronal PAS domain protein 2). PHENOTYPE: Targeted mutation of this gene results in deficits in complex emotional long-term memory tasks [provided by MGI curators] |