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Protein Coding Gene : Uxs1 UDP-glucuronate decarboxylase 1
Primary Identifier  MGI:1915133 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  67883
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable NAD+ binding activity; UDP-glucuronate decarboxylase activity; and protein homodimerization activity. Predicted to be involved in UDP-D-xylose biosynthetic process. Located in mitochondrion. Is expressed in forelimb and hindlimb. Orthologous to human UXS1 (UDP-glucuronate decarboxylase 1).
PHENOTYPE: Mice homozygous for a null allele die prenatally. Heterozygous mice exhibit an increased mean serum IgG2a response to ovalbumin challenge when compared with that of controls. [provided by MGI curators]
  • synonyms:
  • MGI:2138607,
  • 1600025I13Rik,
  • AI451869,
  • AW550562,
  • expressed sequence AI649125,
  • expressed sequence AW550562,
  • UDP-glucuronate decarboxylase 1,
  • MGI:2138257,
  • expressed sequence AI451869,
  • MGI:2138315,
  • AI649125,
  • Uxs1,
  • RIKEN cDNA 1600025I13 gene
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1 Involved In Mutations

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Canonical gene --> Exons in specific strains

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Gene --> Protein-Protein Interactions

Expression

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Phenotype

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Disease

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