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Protein Coding Gene : Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Primary Identifier  MGI:1351352 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  108147
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables IMP cyclohydrolase activity and phosphoribosylaminoimidazolecarboxamide formyltransferase activity. Involved in purine ribonucleoside monophosphate biosynthetic process. Acts upstream of or within cellular response to interleukin-7. Located in mitochondrion. Is expressed in several structures, including alimentary system; heart; nervous system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in purine-pyrimidine metabolic disorder. Orthologous to human ATIC (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase).
  • synonyms:
  • expressed sequence AW212393,
  • Atic,
  • 2610509C24Rik,
  • MGI:2138111,
  • AA536954,
  • MGI:1914741,
  • MGI:2138576,
  • RIKEN cDNA 2610509C24 gene,
  • expressed sequence AA536954,
  • 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase,
  • AW212393
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Features --> Cross References

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0 Canonical

0 CDSs

0 Exons

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2 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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