| Primary Identifier | MGI:1915363 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 108679 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in activation of NF-kappaB-inducing kinase activity; negative regulation of cell population proliferation; and protein modification process. Located in nucleus. Part of COP9 signalosome. Is expressed in several structures, including early embryo; liver; and oocyte. Orthologous to human COPS8 (COP9 signalosome subunit 8). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality, reduced embryonic size and growth, and reduced to absent outgrowth of the inner cell mass of E3.5 embryos. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
