| Primary Identifier | MGI:3644668 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 623503 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable neuropeptide hormone activity and prolactin-releasing peptide receptor binding activity. Acts upstream of or within several processes, including energy reserve metabolic process; fat cell differentiation; and response to insulin. Predicted to be located in cytoplasm. Used to study obesity. Orthologous to human PRLH (prolactin releasing hormone). PHENOTYPE: Homozygous mutation of this gene results in polyphagia; late-onset obesity and adiposity; increase in circulating insulin, leptin, and triglyceride levels; impaired glucose tolerance and insulin resistance; and attenuated responses to the anorexigenic signals cholecystokinin and leptin. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
