| Primary Identifier | MGI:2155936 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 269224 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphatidylinositol binding activity and protein serine/threonine kinase activity. Involved in energy homeostasis; regulation of glucagon secretion; and regulation of respiratory gaseous exchange. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including brain ventricular layer; colon; liver; placenta; and spleen. Orthologous to human PASK (PAS domain containing serine/threonine kinase). PHENOTYPE: Homozygous null mice display resistance to diet-induced obesity, impaired glucose stimulated insulin secretion, abnormal energy balance, and abnormalities in hypoxia induced changes in ventialtion. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
